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New Brunswick is a city in Middlesex County, New Jersey, United States, in the New York City metropolitan area. The city is the county seat of Middlesex County, and the home of Rutgers University. New Brunswick is on the Northeast Corridor rail line, 27 miles (43 km) southwest of Manhattan, on the southern bank of the Raritan River. As of 2016, New Brunswick had a Census-estimated population of 56,910, representing a 3.1% increase from the 55,181 people enumerated at the 2010 United States Census, which in turn had reflected an increase of 6,608 (+13.6%) from the 48,573 counted in the 2000 Census. Due to the concentration of medical facilities in the area, including Robert Wood Johnson University Hospital and Saint Peter's University Hospital, as well as Rutgers, The State University of New Jersey's Robert Wood Johnson Medical School, New Brunswick is known as both the Hub City and the Healthcare City. The corporate headquarters and production facilities of several global pharmaceutical companies are situated in the city, including Johnson & Johnson and Bristol-Myers Squibb.
According to the United States Census Bureau, the city had a total area of 5.789 square miles (14.995 km²), including 5.227 square miles (13.539 km²) of land and 0.562 square miles (1.456 km²) of water (9.71%). New Brunswick is in Raritan Valley (a line of cities in central New Jersey). New Brunswick is on the south side of Raritan Valley along with Piscataway Township, Highland Park, Edison Township, and Franklin Township (Somerset County). New Brunswick lies southwest of Newark and New York City and northeast of Trenton and Philadelphia.